SCHEMBL29973138

SCHEMBL29973138

C1=CC([C@@H]2CCCO2)Oc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1735849 0.82 ABCG2 (0.32) ALDH1A1MAPT
SCHEMBL30407118 0.77 KDM4E (0.35) ALDH1A1MAPT
SCHEMBL1850273 0.76 RORC (0.34) ALDH1A1MAPT
SCHEMBL9506276 0.76 ABCG2 (0.30)
SCHEMBL30912029 0.74 CA2 (0.36)
SCHEMBL31412834 0.73 CHRNB4 (0.43)
SCHEMBL27318735 0.72 ALDH1A1 (0.32) ALDH1A1GAASMN1; SMN2
Hydrochloric Acid SCHEMBL28359865 0.69 HTR2C (0.39)
SCHEMBL30629623 0.69 MAOB (0.48) MAPT
SCHEMBL7048423 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115385876-B Method for constructing C-C bond by photocatalysis activation of alpha-position C-H bond of tetrahydrofuran 中国科学院理化技术研究所 2024-01-30 CN disclosed
CN-115385876-A Method for constructing C-C bond by photocatalytic activation of alpha-position C-H bond of tetrahydrofuran 中国科学院理化技术研究所 2022-11-25 CN disclosed