SCHEMBL9506276

SCHEMBL9506276

C1=CC(C2COO2)Oc2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1735849 0.86 ABCG2 (0.32) ABCG2
SCHEMBL30407118 0.81 KDM4E (0.35) ABCG2
SCHEMBL31412834 0.80 CHRNB4 (0.43) ABCG2
SCHEMBL1850273 0.77 RORC (0.34) ABCG2
SCHEMBL29973138 0.76 ALDH1A1 (0.32)
SCHEMBL30912029 0.74 CA2 (0.36)
SCHEMBL30629623 0.72 MAOB (0.48)
SCHEMBL7048423 0.70
Hydrochloric Acid SCHEMBL28359865 0.69 HTR2C (0.39)
SCHEMBL5100128 0.68 KDM4E (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377729-B1 IMPROVED METHODS OF USING CHEMILUMINESCENT 1,2-DIOXETANES Tropix, Inc. (a Delaware corporation) (US) 1993-08-25 EP disclosed
EP-0377729-A4 IMPROVED METHODS OF USING CHEMILUMINESCENT 1,2-DIOXETANES 1990-12-12 EP disclosed
EP-0377729-A1 IMPROVED METHODS OF USING CHEMILUMINESCENT 1,2-DIOXETANES. TROPIX INC (US) 1990-07-18 EP disclosed
US-4931223-A MIXTURE RELEASING LIGHT OF DIFFERENT WAVELENGTHS BY ENZYME DECOMPOSITION TROPIX, INC. (US) 1990-06-05 US disclosed
WO-1990000168-A1 IMPROVED METHODS OF USING CHEMILUMINESCENT 1,2-DIOXETANES TROPIX, INC. (US) 1990-01-11 WO disclosed