SCHEMBL29973157

SCHEMBL29973157

CC[C@H](C)[C@@H](C(=O)N[C@@H](COC(C)(C)C)C(=O)N(C)[C@@H](Cc1ccccc1)C(=O)N(C)[C@H](C(=O)N[C@@H](CC(=O)OC(C)(C)C)C(=O)O)C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](C)N(C)C(=O)OCc1ccccc1)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
REN P00797 7/20 0.35
CTSD P07339 4/20 0.34
BACE1 P56817 4/20 0.34
CTSK P43235 3/20 0.33
CTSB P07858 2/20 0.33
CTSL P07711 1/20 0.32
CTSS P25774 1/20 0.32
CTSE P14091 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29973342 0.97 REN (0.36) RENCTSDBACE1CTSKCTSB
SCHEMBL29973089 0.96 REN (0.36) RENCTSDBACE1CTSKCTSB
SCHEMBL29973019 0.94 BACE1 (0.38) RENCTSDBACE1CTSKCTSB
SCHEMBL30763321 0.93 BACE1 (0.35) RENCTSDBACE1CTSKCTSB
SCHEMBL29972815 0.89 CTSD (0.38) RENCTSDBACE1CTSE
SCHEMBL29973666 0.89 BACE1 (0.36) CTSDBACE1CTSKCTSBCTSL
SCHEMBL29973674 0.88 REN (0.34) RENCTSDCTSKCTSLCTSS
SCHEMBL30522107 0.87 REN (0.38) RENCTSDBACE1CTSKCTSB
SCHEMBL30763326 0.87 CTSK (0.37) RENCTSDBACE1CTSKCTSB
SCHEMBL29860893 0.85 CTSK (0.38) CTSDBACE1CTSKCTSBCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12331072-B2 Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-06-17 US disclosed
US-20250188116-A1 DEPROTECTION METHOD AND RESIN REMOVAL METHOD IN SOLID-PHASE REACTION FOR PEPTIDE COMPOUND OR AMIDE COMPOUND, AND METHOD FOR PRODUCING PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-06-12 US disclosed
EP-4541787-A1 METHOD FOR PRODUCING O-SUBSTITUTED SERINE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-04-23 EP disclosed
WO-2024024965-A1 METHOD FOR PRODUCING O-SUBSTITUTED SERINE DERIVATIVE 中外製薬株式会社 2024-02-01 WO disclosed
US-20230303619-A1 DEPROTECTION METHOD AND RESIN REMOVAL METHOD IN SOLID-PHASE REACTION FOR PEPTIDE COMPOUND OR AMIDE COMPOUND, AND METHOD FOR PRODUCING PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-09-28 US disclosed
US-11732002-B2 Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-08-22 US disclosed
US-20230056969-A1 METHOD FOR SYNTHESIZING PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-02-23 US disclosed
EP-4083051-A1 METHOD FOR SYNTHESIZING PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11732002-B2 Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound VIP, PEPD, MLN REN 272/4885CTSD 237/4885BACE1 1865/4885
US-12331072-B2 Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound VIP, PEPD, MLN REN 272/4885CTSD 237/4885BACE1 1865/4885
US-20230056969-A1 METHOD FOR SYNTHESIZING PEPTIDE COMPOUND VIP, NGLY1, NPPA REN 780/4885CTSD 194/4885BACE1 336/4885
US-20230303619-A1 DEPROTECTION METHOD AND RESIN REMOVAL METHOD IN SOLID-PHASE REACTION FOR PEPTIDE COMPOUND OR AMIDE COMPOUND, AND METHOD FOR PRODUCING PEPTIDE COMPOUND VIP, PEPD, MLN REN 272/4885CTSD 237/4885BACE1 1865/4885
US-20250188116-A1 DEPROTECTION METHOD AND RESIN REMOVAL METHOD IN SOLID-PHASE REACTION FOR PEPTIDE COMPOUND OR AMIDE COMPOUND, AND METHOD FOR PRODUCING PEPTIDE COMPOUND VIP, PEPD, MLN REN 272/4885CTSD 237/4885BACE1 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.