SCHEMBL31409167

SCHEMBL31409167

COc1ccc(C2Cc3ccccc3C(=O)N2c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.51
NPC1 O15118 3/20 0.51
PKM P14618 1/20 0.51
ABCB1 P08183 2/20 0.50
ALDH1A1 P00352 5/20 0.49
ABAT P80404 1/20 0.46
GAA P10253 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.45
HSD17B10 Q99714 1/20 0.45
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TSHR P16473 1/20 0.44
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
MAOA P21397 1/20 0.44
PTGS2 P35354 1/20 0.44
STING1 Q86WV6 1/20 0.44
GFER P55789 1/20 0.44
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31409141 0.95 ALDH1A1 (0.55) RAB9ANPC1PKMABCB1ALDH1A1
SCHEMBL31409136 0.86 RAB9A (0.47) RAB9ANPC1PKMGAAKMT2A
SCHEMBL8782404 0.83 NPC1 (0.51) RAB9ANPC1PKMALDH1A1GAA
SCHEMBL1997854 0.81 L3MBTL1 (0.56) ALDH1A1ABATGAAKMT2AKDM4E
SCHEMBL29975007 0.81 L3MBTL1 (0.56) ALDH1A1ABATGAAKMT2AKDM4E
SCHEMBL31409139 0.80 HSD11B1 (0.49) RAB9ANPC1ALDH1A1GAAKMT2A
SCHEMBL31409122 0.78 KMT2A (0.53) RAB9ANPC1PKMALDH1A1GAA
SCHEMBL6124201 0.76 TSHR (0.53) RAB9ANPC1ALDH1A1GAAKMT2A
SCHEMBL15841547 0.75 GFER (0.60) ALDH1A1ABATKMT2AMAPTTSHR
SCHEMBL15841548 0.75 GFER (0.60) ALDH1A1ABATKMT2AMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119506909-A Method for electrochemically synthesizing 3, 4-dihydro-isoquinoline-1 (2H) -ketone compound 宜宾学院 2025-02-25 CN disclosed