Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3001051 | 0.83 | TRPM8 (0.34) | MEN1ALDH1A1KMT2A | |
| SCHEMBL19075856 | 0.74 | MEN1 (0.33) | CA14MEN1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6852163 | 0.73 | THRB (0.31) | — | |
| SCHEMBL2997519 | 0.70 | HPGD (0.46) | SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL6770295 | 0.69 | MEN1 (0.32) | MEN1CYP1A2KMT2A | |
| SCHEMBL14371787 | 0.68 | ALDH1A1 (0.33) | SMN1; SMN2CA14MEN1ALDH1A1CYP1A2 | |
| SCHEMBL2994372 | 0.66 | MEN1 (0.30) | MEN1CYP1A2KMT2A | |
| SCHEMBL6771437 | 0.66 | LMNA (0.37) | MEN1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL16229104 | 0.64 | CYP2C19 (0.47) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18022615 | 0.64 | CYP2C19 (0.47) | MEN1ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |