SCHEMBL29975465

SCHEMBL29975465

C1CCC2=NCCCN2CC1.C1CCC2=NCCCN2CC1.O=C(Nc1ccn([C@H]2CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)C[C@@H](CP(=O)(O)O)O2)c(=O)n1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.48
RIN1 Q13671 1/20 0.48
POLB P06746 1/20 0.41
P2RY6 Q15077 2/20 0.40
P2RY14 Q15391 2/20 0.40
NT5E P21589 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.32
INMT O95050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27158214 0.89 ABL1 (0.59) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL29975337 0.85 ABL1 (0.53) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL29975654 0.82 ABL1 (0.36) ABL1RIN1P2RY6SMN1; SMN2
SCHEMBL15090413 0.80 ABL1 (0.70) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL14980414 0.80 ABL1 (0.70) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL29975987 0.80 NT5M (0.38)
SCHEMBL23565661 0.79 ABL1 (0.61) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL27158019 0.79 ABL1 (0.47) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL30937947 0.77 ABL1 (0.53) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL21361135 0.77 ABL1 (0.53) ABL1RIN1POLBP2RY6P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2024-08-01 US claimed
EP-4332111-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND Nippon Shinyaku Co., Ltd. (JP) 2024-03-06 EP claimed
WO-2022230954-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND 日本新薬株式会社 2022-11-03 WO claimed
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2024-08-01 US disclosed
EP-4332111-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND Nippon Shinyaku Co., Ltd. (JP) 2024-03-06 EP disclosed
WO-2022230954-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND 日本新薬株式会社 2022-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND POLRMT, CYC1, MRM1 ABL1 3283/4885RIN1 3783/4885POLB 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.