Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.42 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13535271 | 0.84 | KMT2A (0.49) | ALDH1A1MAPTHTTKDM4EMAPK1 | |
| SCHEMBL27802495 | 0.84 | CHRNB2 (0.51) | ALDH1A1MAPTHTTKDM4EMAPK1 | |
| SCHEMBL27778860 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHTTKDM4EMAPK1 | |
| SCHEMBL27779058 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHTTKDM4EMAPK1 | |
| SCHEMBL27778861 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHTTKDM4EMAPK1 | |
| SCHEMBL5190875 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTKDM4EMAPK1 | |
| SCHEMBL31740140 | 0.81 | SSTR4 (0.53) | — | |
| SCHEMBL13535512 | 0.76 | CHRNB2 (0.56) | ALDH1A1MAPTHTTKDM4EMAPK1 | |
| SCHEMBL12337286 | 0.74 | CCR2 (0.41) | MAPT | |
| SCHEMBL5191569 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12208107-B2 | Method and compositions for the treatment of anemia through the inhibition of furin | BRIGHAM YOUNG UNIVERSITY (US) | 2025-01-28 | — | — | US | disclosed |
| EP-4135740-A1 | AEROSOLIZED FORMULATIONS OF HIV PROTEASE INHIBITORS FOR THE TREATMENT OF AIRWAY REFLUX | The Medical College of Wisconsin, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| US-20230038724-A1 | METHOD AND COMPOSITIONS FOR THE TREATMENT OF ANEMIA THROUGH THE INHIBITION OF FURIN | BRIGHAM YOUNG UNIVERSITY | 2023-02-09 | — | — | US | disclosed |
| US-11458148-B2 | Method and compositions for the treatment of anemia through the inhibition of furin | BRIGHAM YOUNG UNIVERSITY (US) | 2022-10-04 | — | — | US | disclosed |