Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27778860 | 0.91 | ALDH1A1 (0.53) | CHRNB2CHRNA4ALDH1A1MAPTHTT | |
| SCHEMBL27778861 | 0.91 | ALDH1A1 (0.53) | CHRNB2CHRNA4ALDH1A1MAPTHTT | |
| SCHEMBL27779058 | 0.91 | ALDH1A1 (0.53) | CHRNB2CHRNA4ALDH1A1MAPTHTT | |
| SCHEMBL13535271 | 0.90 | KMT2A (0.49) | CHRNB2CHRNA4ALDH1A1MAPTHTT | |
| SCHEMBL5190875 | 0.90 | ALDH1A1 (0.49) | CHRNB2CHRNA4ALDH1A1MAPTHTT | |
| SCHEMBL29976288 | 0.84 | ALDH1A1 (0.44) | CHRNB2CHRNA4ALDH1A1MAPTHTT | |
| SCHEMBL27780998 | 0.84 | SIGMAR1 (0.51) | ALDH1A1KDM4EKMT2ASIGMAR1 | |
| SCHEMBL13535512 | 0.81 | CHRNB2 (0.56) | CHRNB2CHRNA4ALDH1A1MAPTHTT | |
| SCHEMBL5191569 | 0.81 | ALDH1A1 (0.47) | CHRNB2CHRNA4ALDH1A1MAPTHTT | |
| SCHEMBL27802494 | 0.75 | L3MBTL1 (0.52) | ALDH1A1MAPTKDM4EMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101712655-B | Acetamide derivative and application thereof in pharmacy | YINLIN QIN | 2012-05-23 | — | — | CN | disclosed |
| CN-101712655-A | Acetamide derivative and application thereof in pharmacy | YINLIN QIN | 2010-05-26 | — | — | CN | disclosed |