Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.50 |
| ▸ | LPL | P06858 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985633 | 1.00 | LIPG (0.50) | LIPGLPLPOLBNPSR1PRMT5 | |
| SCHEMBL29348714 | 0.85 | LPL (0.48) | LIPGLPLPOLBNPSR1KLKB1 | |
| SCHEMBL3288256 | 0.82 | MAPK14 (0.47) | LIPGLPLPRMT5WDR77MAPK14 | |
| SCHEMBL1684370 | 0.78 | PRMT5 (0.56) | LIPGLPLPOLBNPSR1PRMT5 | |
| SCHEMBL31755824 | 0.78 | PRMT5 (0.56) | LIPGLPLPOLBNPSR1PRMT5 | |
| SCHEMBL9752676 | 0.77 | POLB (0.58) | POLBNPSR1KLKB1KLK1MAPK14 | |
| SCHEMBL20504070 | 0.77 | LPL (0.47) | LIPGLPLPRMT5WDR77MAPK14 | |
| SCHEMBL29640063 | 0.76 | LPL (0.55) | LIPGLPL | |
| SCHEMBL2221017 | 0.76 | LIPG (0.42) | LIPGLPLPRMT5WDR77KEAP1 | |
| SCHEMBL1356694 | 0.76 | LPL (0.55) | LIPGLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | LIPG 2253/4885LPL 3130/4885POLB 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.