Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985662 | 0.73 | SDHB (0.42) | TP53MAPTPDE2APDE3AKMT2A | |
| SCHEMBL19805843 | 0.72 | SDHB (0.55) | TP53MAPTPDE2APDE3ALMNA | |
| SCHEMBL28307456 | 0.70 | SDHB (0.43) | TP53MAPTPDE2APDE3AKMT2A | |
| SCHEMBL19805926 | 0.70 | KDM4E (0.41) | LMNASMN1; SMN2SIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL28306340 | 0.69 | TP53 (0.37) | TP53MAPTPDE2APDE3AKMT2A | |
| SCHEMBL26313133 | 0.67 | SDHB (0.47) | TP53MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL26313137 | 0.64 | SDHB (0.52) | — | |
| SCHEMBL19806009 | 0.63 | L3MBTL1 (0.35) | TP53MAPTKMT2AMEN1LMNA | |
| SCHEMBL22912306 | 0.63 | L3MBTL1 (0.35) | TP53MAPTKMT2AMEN1LMNA | |
| SCHEMBL19805988 | 0.63 | SDHB (0.53) | TP53MAPTPDE2APDE3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |