Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30715310 | 0.80 | TUBB4A (0.43) | L3MBTL1KDM4EHSD11B1ALDH1A1HPGD | |
| SCHEMBL3673992 | 0.74 | HSD11B1 (0.42) | L3MBTL1KDM4EHSD11B1ALDH1A1HPGD | |
| SCHEMBL19343831 | 0.74 | L3MBTL1 (0.41) | L3MBTL1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29463590 | 0.73 | KDM4E (0.69) | KDM4EHSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19249104 | 0.73 | KDM4E (0.53) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL272962 | 0.71 | PDE4B (0.51) | KDM4EHSD11B1ALDH1A1HPGDCXCR2 | |
| SCHEMBL3316267 | 0.71 | STS (0.49) | L3MBTL1KDM4EHSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL364293 | 0.70 | KMT2A (0.49) | L3MBTL1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5569165 | 0.70 | HSD11B1 (0.47) | KDM4EHSD11B1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31393691 | 0.70 | EGFR (0.36) | HSD11B1HPGDSMN1; SMN2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403558-A | Aromatic heterocyclic compound with antitumor activity and preparation method and application thereof | 河南真实生物科技有限公司 | 2022-11-29 | — | — | CN | disclosed |