Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.64 |
| ▸ | NCF1 | P14598 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4828824 | 0.86 | LMNA (0.56) | LMNASMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL3948130 | 0.85 | LMNA (0.55) | LMNASMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL4711940 | 0.84 | LMNA (0.54) | LMNASMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL2925701 | 0.83 | ALDH1A1 (0.59) | LMNASMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL2850013 | 0.82 | ALDH1A1 (0.70) | LMNASMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL6865542 | 0.82 | ALDH1A1 (0.72) | LMNASMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL4838001 | 0.82 | CYP2D6 (0.73) | LMNASMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL3047497 | 0.82 | KDM4E (0.71) | LMNASMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL2930424 | 0.82 | SIGMAR1 (0.73) | LMNASMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL3093924 | 0.82 | FAAH (0.70) | SMN1; SMN2KMT2AMEN1TSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |