Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23354278 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2LTB4RLTB4R2KDM4ECYP1A2 | |
| SCHEMBL7591657 | 0.85 | SMN1; SMN2 (0.75) | SMN1; SMN2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28860337 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2LTB4RLTB4R2CYP2C9ALDH1A1 | |
| SCHEMBL29979794 | 0.83 | CYP2C9 (0.43) | SMN1; SMN2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL23354249 | 0.83 | CYP2C9 (0.43) | SMN1; SMN2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9151080 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8566031 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9683222 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6701301 | 0.81 | SMN1; SMN2 (0.63) | SMN1; SMN2LTB4RLTB4R2KDM4ECYP1A2 | |
| SCHEMBL6778891 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4ECYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398120-B2 | Substituted hydantoinamides as ADAMTS7 antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2025-08-26 | — | — | US | disclosed |
| EP-4058448-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2022-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12398120-B2 | Substituted hydantoinamides as ADAMTS7 antagonists | ADAMTS7, MMP7, ADAM17 | SMN1; SMN2 3850/4885LTB4R 1461/4885LTB4R2 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.