Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874814 | 0.82 | NPC1 (0.55) | CTSKCTSSALDH1A1KCNH2KDM4E | |
| SCHEMBL29979429 | 0.81 | TGFBR1 (0.60) | CTSSKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL4025464 | 0.81 | TGFBR1 (0.60) | CTSSKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL4033214 | 0.79 | TGFBR1 (0.59) | CTSSKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL4183904 | 0.74 | GRM5 (0.70) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL17826986 | 0.74 | KDM4E (0.52) | CTSKCTSSALDH1A1KCNH2KDM4E | |
| SCHEMBL24795073 | 0.74 | SMN1; SMN2 (0.46) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL16629561 | 0.72 | KMO (0.58) | CTSKCTSSALDH1A1LMNAKDM4E | |
| SCHEMBL4446189 | 0.70 | CTSK (0.67) | CTSKCTSSKCNH2CTSLCTSB | |
| SCHEMBL28392301 | 0.70 | ASIC3 (0.48) | ALDH1A1LMNATGFBR1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5022915-A | Substituted 2,4-diarylpyrimidines and their use as herbicides | ICI AMERICAS INC. (US) | 1991-06-11 | — | — | US | disclosed |