Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 11/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874783 | 1.00 | HTT (0.44) | HTTMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3873941 | 0.89 | GPR3 (0.61) | HTTMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL31004968 | 0.89 | GPR3 (0.61) | HTTMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18252670 | 0.87 | ESR1 (0.42) | HTTMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3876723 | 0.87 | ALDH1A1 (0.62) | HTTMAPTALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL4915968 | 0.87 | ALOX15 (0.42) | HTTMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4921472 | 0.87 | ESR1 (0.36) | HTTMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4922476 | 0.87 | BCKDK (0.49) | MAPTALDH1A1KDM4EHSD17B10ESR1 | |
| SCHEMBL15003270 | 0.85 | MAOA (0.49) | HTTMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL24962715 | 0.82 | ESR1 (0.47) | MAPTALDH1A1SMN1; SMN2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160291-A | Dibenzothiophene-based polymerizable compound and preparation method and application thereof | 江苏创拓新材料有限公司 | 2022-10-11 | — | — | CN | disclosed |