Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890001 | 0.88 | AVPR1A (0.51) | DRD4DRD2DRD3AVPR2AVPR1A | |
| SCHEMBL2895059 | 0.86 | THRB (0.57) | DRD4DRD2DRD3AVPR2AVPR1A | |
| SCHEMBL2895772 | 0.85 | ALDH1A1 (0.57) | DRD4DRD2DRD3AVPR2AVPR1A | |
| SCHEMBL2897057 | 0.83 | SMN1; SMN2 (0.55) | AVPR2AVPR1AALDH1A1MEN1HTT | |
| SCHEMBL2895054 | 0.83 | ALDH1A1 (0.53) | AVPR2AVPR1AALDH1A1MEN1HTT | |
| SCHEMBL14534419 | 0.83 | ALDH1A1 (0.53) | AVPR2AVPR1AALDH1A1MEN1HTT | |
| SCHEMBL2895595 | 0.83 | ALDH1A1 (0.56) | AVPR2AVPR1AALDH1A1MEN1HTT | |
| SCHEMBL2895118 | 0.83 | ALDH1A1 (0.56) | AVPR2AVPR1AALDH1A1MEN1HTT | |
| SCHEMBL2896930 | 0.82 | ALDH1A1 (0.52) | AVPR2AVPR1AALDH1A1MEN1HTT | |
| SCHEMBL2897329 | 0.82 | ALDH1A1 (0.52) | AVPR2AVPR1AALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120743-A1 | 11Beta-Hydroxysteroid Dehydrogenase Type 1 Active Compounds | HIGH POINT PHARMACEUTICALS, LLC (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120743-A1 | 11Beta-Hydroxysteroid Dehydrogenase Type 1 Active Compounds | HSD11B1, HSD3B1, HSD17B1 | DRD4 2858/4885DRD2 2577/4885DRD3 2344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.