Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986359 | 0.81 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL28632585 | 0.81 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL29987483 | 0.74 | MAPK14 (0.33) | — | |
| SCHEMBL29986381 | 0.71 | CHRM2 (0.44) | — | |
| SCHEMBL29986352 | 0.70 | THRA (0.33) | — | |
| SCHEMBL28639975 | 0.68 | GPR119 (0.52) | — | |
| SCHEMBL910822 | 0.65 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL910821 | 0.65 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL2239382 | 0.64 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL23159342 | 0.63 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113278013-B | 2, 6-disubstituted 1,2, 4-triazine-3, 5-diketone compound and preparation method and application thereof | 昆药集团股份有限公司 | 2022-09-23 | — | — | CN | disclosed |