Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639975 | 0.80 | GPR119 (0.52) | GPR119 | |
| SCHEMBL28632585 | 0.79 | SLC6A4 (0.38) | — | |
| SCHEMBL29986359 | 0.79 | SLC6A4 (0.38) | — | |
| SCHEMBL29987275 | 0.74 | SLC6A4 (0.42) | — | |
| SCHEMBL29986378 | 0.72 | FPR2 (0.31) | — | |
| SCHEMBL29571300 | 0.72 | GPR119 (0.41) | HRH3GPR119LIPE | |
| SCHEMBL28638133 | 0.72 | HRH4 (0.34) | — | |
| SCHEMBL29986381 | 0.72 | CHRM2 (0.44) | GPR119 | |
| SCHEMBL29571974 | 0.70 | GPR119 (0.40) | HRH3GPR119LIPE | |
| SCHEMBL8511025 | 0.68 | MAPK14 (0.39) | MAPK14HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113278013-B | 2, 6-disubstituted 1,2, 4-triazine-3, 5-diketone compound and preparation method and application thereof | 昆药集团股份有限公司 | 2022-09-23 | — | — | CN | disclosed |