Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287751 | 0.78 | TRPV1 (0.46) | — | |
| Bicarbonate SCHEMBL2854209 | 0.63 | LMNA (0.37) | — | |
| SCHEMBL286981 | 0.61 | TRPV1 (0.73) | — | |
| SCHEMBL3718319 | 0.60 | MEN1 (0.35) | — | |
| SCHEMBL8547992 | 0.60 | MEN1 (0.35) | — | |
| SCHEMBL9222918 | 0.59 | TSHR (0.42) | — | |
| SCHEMBL5381799 | 0.59 | KDM4E (0.37) | — | |
| SCHEMBL11151068 | 0.58 | CYP1A2 (0.30) | — | |
| SCHEMBL2611045 | 0.58 | GABRA1 (0.39) | — | |
| SCHEMBL6846649 | 0.58 | IDO1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427436-A1 | SUBSTITUTED AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127855-A1 | SUBSTITUTED AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2010-11-11 | — | — | WO | disclosed |