SCHEMBL29988558

SCHEMBL29988558

Cc1ccsc1C(=O)NCC(=O)NCC(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MAPT P10636 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GAA P10253 3/20 0.43
PKM P14618 2/20 0.43
NAMPT P43490 1/20 0.43
PPARG P37231 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
LMNA P02545 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
GSK3B P49841 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8791459 0.78 HPGD (0.54) KMT2ANPC1RAB9AL3MBTL1GAA
SCHEMBL7472113 0.77 KMT2A (0.55) KMT2ANPC1RAB9AL3MBTL1GAA
SCHEMBL19457471 0.75 LMNA (0.43) KMT2AL3MBTL1GAANAMPTLMNA
SCHEMBL15741530 0.74 HPGD (0.56) KMT2ANPC1RAB9AGAALMNA
SCHEMBL20988114 0.74 LMNA (0.42) KMT2AL3MBTL1GAALMNAALDH1A1
SCHEMBL3370667 0.74 PKM (0.60) KMT2ANPC1RAB9AL3MBTL1MAPT
SCHEMBL12031648 0.72 RAB9A (0.50) KMT2ANPC1RAB9AL3MBTL1ALDH1A1
SCHEMBL6360579 0.71 NPC1 (0.59) KMT2ANPC1RAB9AL3MBTL1MAPT
SCHEMBL28364538 0.71 KMT2A (0.55) KMT2ANPC1RAB9AL3MBTL1GAA
SCHEMBL31536380 0.70 LMNA (0.46) KMT2ANPC1RAB9AGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220323421-A1 Soft Chewable Veterinary Dosage Form INTERVET INC. (US) 2022-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220323421-A1 Soft Chewable Veterinary Dosage Form SI, GYPA, CYP3A7 KMT2A 427/4885NPC1 2467/4885RAB9A 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.