Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 4/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29987930 | 0.91 | ALDH1A1 (0.47) | MTNR1AMTNR1BMAPTTNKSPARP2 | |
| SCHEMBL29988217 | 0.83 | ALDH1A1 (0.41) | TNKSPARP2RAB9AUSP2HPGD | |
| SCHEMBL29988293 | 0.82 | RAB9A (0.41) | MAPTRAB9AUSP2HPGDTSHR | |
| SCHEMBL29988247 | 0.81 | MTNR1A (0.44) | MTNR1AMTNR1BMAPTTNKSPARP2 | |
| SCHEMBL30578684 | 0.77 | ALOX15B (0.44) | MAPTRAB9AUSP2HPGDTSHR | |
| SCHEMBL30685474 | 0.76 | ALDH1A1 (0.59) | RAB9AUSP2HPGDTSHRNPC1 | |
| SCHEMBL29082339 | 0.76 | ALDH1A1 (0.41) | MAPTTNKSPARP2RAB9AUSP2 | |
| SCHEMBL29082336 | 0.76 | ALDH1A1 (0.41) | MAPTTNKSPARP2RAB9AUSP2 | |
| SCHEMBL30578697 | 0.76 | ALDH1A1 (0.41) | MAPTRAB9AUSP2HPGDTSHR | |
| SCHEMBL24998118 | 0.75 | MTNR1A (0.51) | MTNR1AMTNR1BRAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212902-A1 | MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY | ALTOS LABS, INC. (US) | 2022-10-06 | — | — | WO | disclosed |