Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22806920 | 0.86 | KDM4E (0.45) | CYP19A1RAB9AGAAL3MBTL1MAPK1 | |
| SCHEMBL3433366 | 0.83 | JAK1 (0.40) | DHODHLMNANPY5RMEN1KMT2A | |
| SCHEMBL29384916 | 0.83 | JAK1 (0.40) | DHODHLMNANPY5RMEN1KMT2A | |
| SCHEMBL17865581 | 0.81 | FBP1 (0.57) | DHODHPOLBMEN1KMT2AFBP1 | |
| SCHEMBL3415905 | 0.79 | DHODH (0.36) | DHODHRAB9AGAAL3MBTL1MAPK1 | |
| SCHEMBL22807011 | 0.78 | HRH4 (0.42) | CYP19A1GAAL3MBTL1MAPK1LMNA | |
| SCHEMBL22806895 | 0.77 | CYP19A1 (0.46) | DHODHCYP19A1RAB9APOLBNPY5R | |
| SCHEMBL3008832 | 0.77 | CYP19A1 (0.46) | DHODHCYP19A1POLBMEN1KMT2A | |
| SCHEMBL2995350 | 0.77 | CYP19A1 (0.46) | DHODHCYP19A1RAB9APOLBNPY5R | |
| SCHEMBL1897623 | 0.76 | CSF1R (0.42) | DHODHRAB9AGAAMAPK1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114080382-B | Process for preparing indole or indazole compounds | 株式会社LG化学 | 2024-05-24 | — | — | CN | claimed |
| EP-3971184-B1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | LG CHEMICAL LTD (KR) | 2024-04-03 | — | — | EP | claimed |
| EP-3971184-A1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | LG Chem, Ltd. (KR) | 2022-03-23 | — | — | EP | claimed |
| CN-114080382-A | Process for preparing indole or indazole compounds | 株式会社LG化学 | 2022-02-22 | — | — | CN | claimed |
| CN-114080386-B | Process for preparing indole or indazole compounds | 株式会社LG化学 | 2024-05-31 | — | — | CN | disclosed |
| CN-114080382-B | Process for preparing indole or indazole compounds | 株式会社LG化学 | 2024-05-24 | — | — | CN | disclosed |
| EP-3971185-B1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | LG CHEMICAL LTD (KR) | 2024-04-17 | — | — | EP | disclosed |
| EP-3971184-B1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | LG CHEMICAL LTD (KR) | 2024-04-03 | — | — | EP | disclosed |
| CN-114096534-B | Process for preparing indole or indazole compounds | 株式会社LG化学 | 2024-01-02 | — | — | CN | disclosed |
| EP-3971186-B1 | PREPARATION METHOD FOR INDOLE OR INDAZOLE COMPOUND | LG CHEMICAL LTD (KR) | 2023-08-02 | — | — | EP | disclosed |
| EP-3971186-A1 | PREPARATION METHOD FOR INDOLE OR INDAZOLE COMPOUND | LG Chem, Ltd. (KR) | 2022-03-23 | — | — | EP | disclosed |
| EP-3971185-A1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | LG Chem, Ltd. (KR) | 2022-03-23 | — | — | EP | disclosed |
| US-8349885-B2 | Indole and indazole derivatives having a cell-, tissue- and organ-preserving effect | LG LIFE SCIENCES LTD. (KR) | 2013-01-08 | — | — | US | disclosed |
| US-20120270203-A1 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | LG CHEM, LTD. (KR) | 2012-10-25 | — | — | US | disclosed |
| US-20100291533-A1 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | LG LIFE SCIENCES LTD. (KR) | 2010-11-18 | — | — | US | disclosed |
| EP-2230238-A2 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | LG Life Sciences Ltd. (KR) | 2010-09-22 | — | — | EP | disclosed |
| US-20100197673-A1 | INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS | LG LIFE SCIENCES LTD (KR) | 2010-08-05 | — | — | US | disclosed |
| CN-101784543-A | Indole and indazole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2010-07-21 | — | — | CN | disclosed |
| EP-2178870-A1 | INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS | LG Life Sciences Ltd. (KR) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009025478-A1 | INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS | LG LIFE SCIENCES LTD. (KR) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270203-A1 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | IDO1, IDO2, INMT | DHODH 2870/4885CYP19A1 969/4885RAB9A 3325/4885 |
| US-20100197673-A1 | INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS | IDO1, IDO2, NFATC1 | DHODH 1097/4885CYP19A1 2038/4885RAB9A 3616/4885 |
| US-20100291533-A1 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | IDO1, IDO2, INMT | DHODH 2870/4885CYP19A1 969/4885RAB9A 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.