SCHEMBL1897623

SCHEMBL1897623

O=S1(=O)CCN(Cc2cc(NC3CCOCC3)c3[nH]c(-c4ccccc4)cc3c2)CC1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 4/20 0.42
VCP P55072 2/20 0.39
PARP14 Q460N5 1/20 0.36
MAPK1 P28482 3/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
RAB9A P51151 1/20 0.36
NPY5R Q15761 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
ADORA2B P29275 2/20 0.34
ADORA3 P0DMS8 1/20 0.34
ADORA1 P30542 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
HDAC1 Q13547 1/20 0.34
DHODH Q02127 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386984 1.00 CSF1R (0.42) CSF1RVCPPARP14MAPK1MAPT
Sulfuric Acid SCHEMBL30014339 0.96 CSF1R (0.39) CSF1RVCPPARP14MAPK1MAPT
SCHEMBL25332392 0.91 CSF1R (0.42) CSF1RVCPPARP14MAPK1MAPT
SCHEMBL2995328 0.91 VCP (0.39) CSF1RVCPRAB9AADORA1DRD2
SCHEMBL29936652 0.91 VCP (0.39) CSF1RVCPRAB9AADORA1DRD2
SCHEMBL3415437 0.90 VCP (0.40) VCPMAPK1MAPTPKMRAB9A
SCHEMBL3000481 0.89 ACP1 (0.41) CSF1RPKMKDM4EDRD4
SCHEMBL31043039 0.88 CSF1R (0.43) CSF1RVCPNPY5RKDM4EDRD2
SCHEMBL1897985 0.88 CSF1R (0.43) CSF1RVCPNPY5RKDM4EDRD2
SCHEMBL31022317 0.87 VCP (0.39) CSF1RVCPMAPK1NPY5RKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213583-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF MITOIMMUNE THERAPEUTICS INC. (KR) 2025-07-03 US claimed
US-20250082646-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF MITOIMMUNE THERAPEUTICS INC. (KR) 2025-03-13 US claimed
EP-4470541-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF MitoImmune Therapeutics Inc. (KR) 2024-12-04 EP claimed
US-20240374646-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME MITOIMMUNE THERAPEUTICS INC. (KR) 2024-11-14 US claimed
WO-2024191106-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF EPILEPSY 주식회사 미토이뮨테라퓨틱스 2024-09-19 WO claimed
CN-118647383-A Anti-ovarian aging pharmaceutical composition and application thereof 水疗免疫疗法有限公司 2024-09-13 CN claimed
US-20240269145-A1 USE OF INDOLE COMPOUND AS INHIBITORS OF FERROPTOSIS MITOIMMUNE THERAPEUTICS INC. (KR) 2024-08-15 US claimed
EP-4382106-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME MitoImmune Therapeutics Inc. (KR) 2024-06-12 EP claimed
WO-2023182840-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF 주식회사 미토이뮨테라퓨틱스 2023-09-28 WO claimed
WO-2023146341-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF 주식회사 미토이뮨테라퓨틱스 2023-08-03 WO claimed
US-20150038500-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING OPHTHALMIC DISORDERS CATHOLIC UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-02-05 US claimed
EP-2230238-B1 INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT LG LIFE SCIENCES LTD (KR) 2013-12-11 EP claimed
US-8436038-B2 Indole and indazole compounds as an inhibitor of cellular necrosis LG LIFE SCIENCES LTD. (KR) 2013-05-07 US claimed
US-8349885-B2 Indole and indazole derivatives having a cell-, tissue- and organ-preserving effect LG LIFE SCIENCES LTD. (KR) 2013-01-08 US claimed
US-20120270203-A1 INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT LG CHEM, LTD. (KR) 2012-10-25 US claimed
US-20100291533-A1 INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT LG LIFE SCIENCES LTD. (KR) 2010-11-18 US claimed
EP-2230238-A2 INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT LG Life Sciences Ltd. (KR) 2010-09-22 EP claimed
US-20100197673-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG LIFE SCIENCES LTD (KR) 2010-08-05 US claimed
EP-2178870-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG Life Sciences Ltd. (KR) 2010-04-28 EP claimed
WO-2009025478-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG LIFE SCIENCES LTD. (KR) 2009-02-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240374646-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME TFAM, FIS1, AIFM1 CSF1R 1534/4885VCP 1138/4885PARP14 4300/4885
US-20250082646-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF CYP19A1, NR5A1, CYP11A1 CSF1R 4503/4885VCP 602/4885PARP14 2752/4885
US-20250213583-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF ZC3HAV1, ZC3HAV1L, SARS1 CSF1R 3618/4885VCP 2469/4885PARP14 4358/4885
US-20120270203-A1 INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT IDO1, IDO2, INMT CSF1R 2444/4885VCP 4243/4885PARP14 3292/4885
US-20100197673-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS IDO1, IDO2, NFATC1 CSF1R 2910/4885VCP 3548/4885PARP14 2120/4885
US-20150038500-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING OPHTHALMIC DISORDERS AQP1, EYA3, SF1 CSF1R 3822/4885VCP 2813/4885PARP14 4817/4885
US-20100291533-A1 INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT IDO1, IDO2, INMT CSF1R 2444/4885VCP 4243/4885PARP14 3292/4885
US-20240269145-A1 USE OF INDOLE COMPOUND AS INHIBITORS OF FERROPTOSIS AIFM2, FECH, SLC40A1 CSF1R 1524/4885VCP 3822/4885PARP14 4221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.