Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384916 | 1.00 | JAK1 (0.40) | JAK1DHODHLMNAKMT2AMEN1 | |
| SCHEMBL25924580 | 0.86 | JAK2 (0.44) | JAK1DHODHKMT2AMEN1NPY5R | |
| SCHEMBL27182356 | 0.84 | L3MBTL1 (0.40) | KMT2AMEN1NPY5RKDM4EALDH1A1 | |
| SCHEMBL3011386 | 0.83 | ALDH1A1 (0.43) | JAK1DHODHKDM4EALDH1A1ACP1 | |
| SCHEMBL2999222 | 0.83 | DHODH (0.39) | DHODHLMNAKMT2AMEN1VCP | |
| SCHEMBL2995348 | 0.79 | VCP (0.35) | JAK1DHODHLMNAKMT2AMEN1 | |
| SCHEMBL3415437 | 0.78 | VCP (0.40) | DHODHKMT2AMEN1VCPCYP2C19 | |
| SCHEMBL29386984 | 0.77 | CSF1R (0.42) | DHODHVCPNPY5RDRD2DRD4 | |
| SCHEMBL1897623 | 0.77 | CSF1R (0.42) | DHODHVCPNPY5RDRD2DRD4 | |
| SCHEMBL3014664 | 0.77 | DHODH (0.38) | DHODHLMNAVCPNPY5RDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114080382-B | Process for preparing indole or indazole compounds | 株式会社LG化学 | 2024-05-24 | — | — | CN | claimed |
| EP-3971184-B1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | LG CHEMICAL LTD (KR) | 2024-04-03 | — | — | EP | claimed |
| EP-3971184-A1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | LG Chem, Ltd. (KR) | 2022-03-23 | — | — | EP | claimed |
| CN-114080382-A | Process for preparing indole or indazole compounds | 株式会社LG化学 | 2022-02-22 | — | — | CN | claimed |
| WO-2020256429-A1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | 주식회사 엘지화학 | 2020-12-24 | — | — | WO | claimed |
| CN-114080386-B | Process for preparing indole or indazole compounds | 株式会社LG化学 | 2024-05-31 | — | — | CN | disclosed |
| CN-114080382-B | Process for preparing indole or indazole compounds | 株式会社LG化学 | 2024-05-24 | — | — | CN | disclosed |
| EP-3971185-B1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | LG CHEMICAL LTD (KR) | 2024-04-17 | — | — | EP | disclosed |
| EP-3971184-B1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | LG CHEMICAL LTD (KR) | 2024-04-03 | — | — | EP | disclosed |
| CN-114096534-B | Process for preparing indole or indazole compounds | 株式会社LG化学 | 2024-01-02 | — | — | CN | disclosed |
| EP-3971186-B1 | PREPARATION METHOD FOR INDOLE OR INDAZOLE COMPOUND | LG CHEMICAL LTD (KR) | 2023-08-02 | — | — | EP | disclosed |
| EP-3971186-A1 | PREPARATION METHOD FOR INDOLE OR INDAZOLE COMPOUND | LG Chem, Ltd. (KR) | 2022-03-23 | — | — | EP | disclosed |
| WO-2020256429-A1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | 주식회사 엘지화학 | 2020-12-24 | — | — | WO | disclosed |
| WO-2020256432-A1 | METHOD FOR PREPARING INDOLE OR INDAZOLE COMPOUND | 주식회사 엘지화학 | 2020-12-24 | — | — | WO | disclosed |
| WO-2020256437-A1 | PREPARATION METHOD FOR INDOLE OR INDAZOLE COMPOUND | 주식회사 엘지화학 | 2020-12-24 | — | — | WO | disclosed |
| EP-2230238-B1 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | LG LIFE SCIENCES LTD (KR) | 2013-12-11 | — | — | EP | disclosed |
| US-8349885-B2 | Indole and indazole derivatives having a cell-, tissue- and organ-preserving effect | LG LIFE SCIENCES LTD. (KR) | 2013-01-08 | — | — | US | disclosed |
| US-20120270203-A1 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | LG CHEM, LTD. (KR) | 2012-10-25 | — | — | US | disclosed |
| US-20100291533-A1 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | LG LIFE SCIENCES LTD. (KR) | 2010-11-18 | — | — | US | disclosed |
| EP-2230238-A2 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | LG Life Sciences Ltd. (KR) | 2010-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270203-A1 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | IDO1, IDO2, INMT | JAK1 279/4885DHODH 2870/4885LMNA 1945/4885 |
| US-20100291533-A1 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | IDO1, IDO2, INMT | JAK1 279/4885DHODH 2870/4885LMNA 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.