SCHEMBL29993458

SCHEMBL29993458

Ic1ccccc1-c1cccc(-c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.47
PTGER1 P34995 1/20 0.44
PTGER4 P35408 1/20 0.44
PTGER3 P43115 1/20 0.44
PTGER2 P43116 1/20 0.44
MAOA P21397 1/20 0.43
ALDH1A1 P00352 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
APAF1 O14727 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
XBP1 P17861 1/20 0.41
PTBP1 P26599 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2562920 1.00 KMO (0.47) KMOPTGER1PTGER4PTGER3PTGER2
SCHEMBL20698262 0.93 KMO (0.37) KMOPTGER1PTGER4PTGER3PTGER2
SCHEMBL26256002 0.88 ALDH1A1 (0.43) KMOPTGER1PTGER4PTGER3PTGER2
SCHEMBL24839914 0.88 KMO (0.41) KMOPTGER1PTGER4PTGER3PTGER2
SCHEMBL21149111 0.87 METAP2 (0.42) KMOPTGER1PTGER4PTGER3PTGER2
SCHEMBL21730829 0.86 DHODH (0.43) KMOPTGER1PTGER4PTGER3PTGER2
SCHEMBL27449581 0.86 HSD17B10 (0.50) KMOMAOAALDH1A1MEN1KMT2A
SCHEMBL21730833 0.84 ENPP3 (0.44) ALDH1A1KMT2ANPC1MAPTRAB9A
SCHEMBL6830189 0.83 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AAPAF1NPC1
SCHEMBL30451343 0.83 ALDH1A1 (0.48) ALDH1A1PRSS1MGLLHDAC8HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335382-A Material for organic electroluminescent device 默克专利有限公司 2022-11-11 CN disclosed