Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1916739 | 0.73 | ARG1 (0.34) | MAPT | |
| SCHEMBL3003340 | 0.71 | PKM (0.34) | — | |
| SCHEMBL27886351 | 0.69 | DGAT1 (0.34) | MAPT | |
| SCHEMBL30343873 | 0.68 | DGAT1 (0.34) | MAPT | |
| SCHEMBL12138536 | 0.68 | DGAT1 (0.34) | — | |
| SCHEMBL27648746 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL3174371 | 0.66 | DGAT1 (0.38) | MAPT | |
| SCHEMBL365038 | 0.66 | DGAT1 (0.38) | MAPT | |
| SCHEMBL7427181 | 0.66 | DGAT1 (0.31) | — | |
| SCHEMBL28319768 | 0.65 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550745-B2 | Method for preparing 4-aminobut-2-enolides | BAYER CROPSCIENCE AG (DE) | 2017-01-24 | — | — | US | disclosed |
| US-20120323023-A1 | METHOD FOR PREPARING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2012-12-20 | — | — | US | disclosed |
| US-8273904-B2 | Method for preparing 4-aminobut-2-enolides | BAYER CROPSCIENCE AG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-20100190990-A1 | Method for Producing 4-Aminobut-2-Enolides | BAYER CROPSCIENCE AG (DE) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190990-A1 | Method for Producing 4-Aminobut-2-Enolides | TUBB4B, UGT2B7, TUBB4A | MAPT 3053/4885 |
| US-20120323023-A1 | METHOD FOR PREPARING 4-AMINOBUT-2-ENOLIDES | UGT2B7, TUBB4B, CYP1B1 | MAPT 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.