Water

Water

SCHEMBL2999771

O.O=C=NS(=O)(=O)N=C=O.O=[SH2]=O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27454116 0.90
Water SCHEMBL27280625 0.90
Hydrochloric Acid SCHEMBL5117795 0.83
Fluoride SCHEMBL27278049 0.83
Ammonia Solution, Strong SCHEMBL27689531 0.83
Hydrochloric Acid SCHEMBL11026696 0.80
Ethane SCHEMBL11317426 0.80 TSHR (0.44)
Benzene SCHEMBL3066248 0.78
SCHEMBL10887154 0.75
Propane SCHEMBL11307246 0.75 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355055-A Isocyanate modified polyimide resin, resin composition containing the same, and cured product thereof 日本化药株式会社 2024-07-16 CN disclosed
WO-2023187625-A1 ADHESIVE-ATTACHED METAL SUBSTRATE AND LAMINATE 藤森工業株式会社 2023-10-05 WO disclosed
WO-2023187624-A1 ADHESIVE-EQUIPPED METAL SUBSTRATE AND LAMINATE 藤森工業株式会社 2023-10-05 WO disclosed
WO-2023112849-A1 ISOCYANATE-MODIFIED POLYIMIDE RESIN, AND RESIN COMPOSITION CONTAINING SAID ISOCYANATE-MODIFIED POLYIMIDE RESIN AND CURED PRODUCT OF SAME 日本化薬株式会社 2023-06-22 WO disclosed
CN-115777003-A Isocyanate-modified polyimide resin, resin composition, and cured product thereof 日本化药株式会社 2023-03-10 CN disclosed
CN-108572514-B Photosensitive resin composition, cured product, substrate, and article 日本化药株式会社 2022-08-23 CN disclosed
WO-2022004583-A1 ISOCYANATE-MODIFIED POLYIMIDE RESIN, RESIN COMPOSITION AND CURED PRODUCT OF SAME 日本化薬株式会社 2022-01-06 WO disclosed
CN-106681104-B Photosensitive resin composition and method for producing same, light shielding film and method for producing same, and liquid crystal display device and method for producing same 日铁化学材料株式会社 2021-06-15 CN disclosed
CN-105527793-B Photosensitive resin composition and cured product thereof 日本化药株式会社 2020-07-28 CN disclosed
CN-108572514-A Photosensitive polymer combination, hardening thing, base material and article 日本化药株式会社 2018-09-25 CN disclosed
CN-106681104-A A photosensitive resin composition, a manufacturing method thereof, a light-shielding film, a manufacturing method of the light-shielding film, a liquid crystal display and a manufacturing method of the liquid crystal display 新日铁住金化学株式会社 2017-05-17 CN disclosed
CN-105527793-A Photosensitive resin composition and hardening substance thereof NIPPON KAYAKU KK 2016-04-27 CN disclosed
US-7781147-B2 Imide-urethane resin, photosensitive resin composition including the same and cured product NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-08-24 US disclosed
US-20090202793-A1 Photosensitive, Aqueous Alkaline Solution-Soluble Polyimide Resin and Photosensitive Resin Composition Containing the same NIPPON KAYAKU KABUSHIKI KAISHA 2009-08-13 US disclosed
US-20080268373-A1 Imide-Urethane Resin, Photosensitive Resin Composition Including the Same and Cured Product NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-10-30 US disclosed
CN-101268418-A Photosensitive resin composition and cured object obtained therefrom NIPPON KAYAKU KK (JP) 2008-09-17 CN disclosed
US-20070161100-A1 Photosensitive resin composition and cured product thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-07-12 US disclosed
EP-1715381-A1 PHOTOSENSITIVE RESIN COMPOSITION AND CURED PRODUCT THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2006-10-25 EP disclosed