Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 4/20 | 0.34 |
| ▸ | DDO | Q99489 | 3/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5771313 | 0.78 | GRIN2D (0.49) | IDO1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5770077 | 0.76 | GRIN2D (0.39) | IDO1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5768535 | 0.75 | RHEB (0.51) | IDO1IMPDH2IMPDH1HRH4DAO | |
| SCHEMBL2000625 | 0.74 | LOXL2 (0.53) | IDO1HRH4MTNR1AMTNR1B | |
| SCHEMBL28352953 | 0.74 | IMPDH2 (0.43) | IDO1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5769848 | 0.74 | DAO (0.50) | IDO1IMPDH2IMPDH1HRH4DAO | |
| SCHEMBL8088130 | 0.71 | CTSV (0.44) | IDO1IMPDH2IMPDH1HRH4DAO | |
| SCHEMBL30120739 | 0.71 | HTR2C (0.45) | IDO1IMPDH2IMPDH1HRH4DAO | |
| SCHEMBL9534359 | 0.70 | KDM4E (0.46) | IDO1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9587971 | 0.70 | ASH1L (0.44) | IDO1IMPDH2IMPDH1HRH4DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197708-A1 | INDOLE COMPOUNDS | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197708-A1 | INDOLE COMPOUNDS | IDO1, IDO2, TPH2 | IDO1 1/4885GRIN2D 1616/4885GRIN3B 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.