Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002400 | 0.89 | KDM4E (0.39) | PDE10ACSF1RPIK3CDHPGDSMPO | |
| SCHEMBL28892709 | 0.89 | KDM4E (0.39) | PDE10ACSF1RPIK3CDHPGDSMPO | |
| SCHEMBL30002600 | 0.83 | HTR1A (0.41) | ALDH1A1LMNAHPGD | |
| SCHEMBL28892764 | 0.83 | HTR1A (0.41) | ALDH1A1LMNAHPGD | |
| SCHEMBL30002661 | 0.81 | MTNR1A (0.43) | PDE10AMPO | |
| SCHEMBL30002421 | 0.81 | MEN1 (0.47) | PDE10ACSF1RALDH1A1 | |
| SCHEMBL28892235 | 0.80 | HTR2A (0.44) | PDE10ACSF1RMPOALDH1A1 | |
| SCHEMBL30002031 | 0.78 | DHFR (0.38) | CSF1RDHFRPARP10MPOPARP15 | |
| SCHEMBL28892526 | 0.78 | SCN1A (0.47) | PDE10APARP10MPOPARP15 | |
| SCHEMBL30002548 | 0.78 | SCN1A (0.47) | PDE10APARP10MPOPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |