Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892709 | 1.00 | KDM4E (0.39) | KDM4EPSMD14COPS5PDE10APARP1 | |
| SCHEMBL30002480 | 0.89 | PDE10A (0.38) | PDE10APIK3CDCSF1RHPGDSMPO | |
| SCHEMBL30002421 | 0.83 | MEN1 (0.47) | KDM4EPDE10ASLC40A1CSF1R | |
| SCHEMBL30002629 | 0.83 | HTR1A (0.41) | KDM4EPSMD14COPS5SMN1; SMN2 | |
| SCHEMBL30002661 | 0.81 | MTNR1A (0.43) | PDE10AMPO | |
| SCHEMBL30002609 | 0.79 | TDP1 (0.40) | KDM4EPDE10ACSF1RMPOSMN1; SMN2 | |
| SCHEMBL28892336 | 0.79 | SMN1; SMN2 (0.36) | KDM4EPDE10ACSF1RMPOTP53 | |
| SCHEMBL28892313 | 0.79 | TDP1 (0.40) | KDM4EPDE10ACSF1RMPOSMN1; SMN2 | |
| SCHEMBL30002031 | 0.78 | DHFR (0.38) | CSF1RMPOSMN1; SMN2 | |
| SCHEMBL30002548 | 0.78 | SCN1A (0.47) | PDE10AMPOSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |