Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.60 |
| ▸ | TUBB | P07437 | 2/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463471 | 1.00 | KDM4E (0.61) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL2880010 | 0.89 | KDM4E (0.66) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL5270788 | 0.86 | RAB9A (0.57) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL3103611 | 0.86 | KDM4E (0.59) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL753833 | 0.85 | TUBB4A (0.60) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL6643173 | 0.83 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL8412387 | 0.82 | HTR6 (0.65) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL754726 | 0.82 | HTR6 (0.62) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL3276393 | 0.82 | TUBB4A (0.67) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL7534562 | 0.82 | ALDH1A1 (0.71) | KDM4EHTR6TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214519-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-10-13 | — | — | WO | disclosed |