Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.60 |
| ▸ | TUBB | P07437 | 2/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002774 | 1.00 | KDM4E (0.61) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL2880010 | 0.89 | KDM4E (0.66) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL5270788 | 0.86 | RAB9A (0.57) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL3103611 | 0.86 | KDM4E (0.59) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL753833 | 0.85 | TUBB4A (0.60) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL6643173 | 0.83 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL8412387 | 0.82 | HTR6 (0.65) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL754726 | 0.82 | HTR6 (0.62) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL3276393 | 0.82 | TUBB4A (0.67) | KDM4EHTR6TUBB4ATUBBTUBA3C | |
| SCHEMBL7534562 | 0.82 | ALDH1A1 (0.71) | KDM4EHTR6TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389008-A1 | 4-QUINOLINONE ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-12-08 | — | — | US | disclosed |
| WO-2021063914-A1 | 4-QUINOLINONE ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-04-08 | — | — | WO | disclosed |
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-7183412-B2 | Ester or amide derivatives | ASTELLAS PHARMA INC. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1583745-A1 | 1-PROPANOL AND 1-PROPYLAMINE DERIVATIVES AND THEIR USE AS GLUCOCORTICOID LIGANDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-10-12 | — | — | EP | disclosed |
| US-20050090497-A1 | Novel ester or amide derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2005-04-28 | — | — | US | disclosed |
| US-6822098-B2 | CARBOCYCLIC CARBO, OXO AMINES SUCH AS N-HEPTYL-3-METHYL-4-OXO -1,4-DIHYDROQUINOLINE-2-CARBOXAMIDE, USED FOR PROPHYLAXIS OF GASTROINTERSTINAL DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20040162321-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-08-19 | — | — | US | disclosed |
| WO-2004063163-A1 | 1-PROPANOL AND 1-PROPYLAMINE DERIVATIVES AND THEIR USE AS GLUCOCORTICOID LIGANDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-07-29 | — | — | WO | disclosed |
| US-20040019214-A1 | Novel ester or amide derivatives | ASTELLAS PHARMA INC. (JP) | 2004-01-29 | — | — | US | disclosed |
| EP-1314726-A1 | NOVEL ESTER OR AMIDE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019214-A1 | Novel ester or amide derivatives | CYP3A7, UGT2B7, NAT1 | KDM4E 1866/4885HTR6 3864/4885TUBB4A 2031/4885 |
| US-20040162321-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | NR3C1, NR3C2, MC2R | KDM4E 3530/4885HTR6 837/4885TUBB4A 2455/4885 |
| US-20050090497-A1 | Novel ester or amide derivatives | CYP3A7, CYP7A1, UGT2B7 | KDM4E 2052/4885HTR6 3906/4885TUBB4A 2219/4885 |
| US-20220389008-A1 | 4-QUINOLINONE ANTIBACTERIAL COMPOUNDS | NQO2, NDUFS3, QARS1 | KDM4E 1533/4885HTR6 4398/4885TUBB4A 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.