SCHEMBL3000368

SCHEMBL3000368

NC(=O)Cc1cccc(S(N)(=O)=O)c1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 14/20 0.57
CA2 P00918 14/20 0.57
CA12 O43570 8/20 0.50
CA9 Q16790 8/20 0.50
CA14 Q9ULX7 3/20 0.50
CA4 P22748 2/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
NOS1 P29475 1/20 0.49
MAPT P10636 1/20 0.46
CA5A P35218 4/20 0.46
CA7 P43166 4/20 0.46
CA5B Q9Y2D0 4/20 0.46
CA3 P07451 1/20 0.45
CA6 P23280 1/20 0.45
CA13 Q8N1Q1 1/20 0.45
ALDH1A1 P00352 1/20 0.44
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4026429 0.87 CA1 (0.55) CA1CA2CA12CA9CA14
SCHEMBL7135778 0.86 CA2 (0.53) CA1CA2CA12CA9CA14
SCHEMBL12984975 0.84 ALDH1A1 (0.50) CA2ALDH1A1
SCHEMBL5634312 0.83 CA2 (0.50) CA1CA2CA12CA9CA14
SCHEMBL16755440 0.83 MEN1 (0.54) CA1CA2CA12CA9CA14
SCHEMBL14514084 0.83 CA2 (0.50) CA1CA2CA12CA9CA14
SCHEMBL16880298 0.82 PSIP1 (0.47) CA2ALDH1A1
SCHEMBL10339219 0.82 CA2 (0.54) CA2ALDH1A1
SCHEMBL14289776 0.82 CA2 (0.54) CA1CA2CA12CA9CA14
SCHEMBL397249 0.82 CA1 (0.48) CA1CA2CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000678-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING, SUPPRESSING, OR TREATING SYMPTOM ASSOCIATED WITH PSEUDO-ALLERGIC REACTION TAKASAKI UNIV OF HEALTH AND WELFARE (JP) 2026-01-01 US claimed
EP-4501357-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR SUPPRESSING OR TREATING SYMPTOMS ACCOMPANYING PSEUDO-ALLERGIC REACTIONS Takasaki University of Health and Welfare (JP) 2025-02-05 EP claimed
WO-2023190826-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR SUPPRESSING OR TREATING SYMPTOMS ACCOMPANYING PSEUDO-ALLERGIC REACTIONS 学校法人 高崎健康福祉大学 2023-10-05 WO claimed
US-20260000678-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING, SUPPRESSING, OR TREATING SYMPTOM ASSOCIATED WITH PSEUDO-ALLERGIC REACTION TAKASAKI UNIV OF HEALTH AND WELFARE (JP) 2026-01-01 US disclosed
EP-4501357-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR SUPPRESSING OR TREATING SYMPTOMS ACCOMPANYING PSEUDO-ALLERGIC REACTIONS Takasaki University of Health and Welfare (JP) 2025-02-05 EP disclosed
WO-2023190826-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR SUPPRESSING OR TREATING SYMPTOMS ACCOMPANYING PSEUDO-ALLERGIC REACTIONS 学校法人 高崎健康福祉大学 2023-10-05 WO disclosed
CN-107922345-A Arylsulfonamide compounds and its therapeutical uses as carbonic anhydrase inhibitor 圣诺康生命科学公司 2018-04-17 CN disclosed
US-20100189685-A1 Antiviral Drugs for Treatment or Prevention of Dengue Infection SIGA TECHNOLOGIES, INC. 2010-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100189685-A1 Antiviral Drugs for Treatment or Prevention of Dengue Infection EIF2AK2, HAVCR2, SNRPE CA1 3245/4885CA2 4373/4885CA12 4083/4885
US-20260000678-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING, SUPPRESSING, OR TREATING SYMPTOM ASSOCIATED WITH PSEUDO-ALLERGIC REACTION TRPV1, TRPV4, TRPV5 CA1 1289/4885CA2 85/4885CA12 1520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.