Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870554 | 0.78 | RIPK1 (0.50) | L3MBTL1POLBHPGDALDH1A1USP2 | |
| SCHEMBL2719543 | 0.74 | — | — | |
| SCHEMBL3159042 | 0.73 | LMNA (0.68) | L3MBTL1POLBHPGDALDH1A1HDAC8 | |
| SCHEMBL885325 | 0.73 | POLB (0.68) | L3MBTL1POLBHPGDALDH1A1USP2 | |
| SCHEMBL3451518 | 0.73 | KMT2A (0.48) | L3MBTL1POLBHPGDALDH1A1HDAC8 | |
| SCHEMBL1709286 | 0.72 | POLB (0.62) | POLBHPGDALDH1A1USP2GAA | |
| Hydrochloric Acid SCHEMBL28571763 | 0.72 | KMT2A (0.66) | L3MBTL1POLBHPGDALDH1A1KMT2A | |
| SCHEMBL3679679 | 0.72 | RIPK1 (0.44) | L3MBTL1POLBHPGDALDH1A1USP2 | |
| SCHEMBL20363212 | 0.72 | RIPK1 (0.58) | L3MBTL1POLBHPGDALDH1A1USP2 | |
| SCHEMBL4752721 | 0.71 | POLB (0.56) | POLBHPGDALDH1A1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190824-A1 | Novel Substituted Piperidones as HSP Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190824-A1 | Novel Substituted Piperidones as HSP Inducers | HSF1, HSPA4, HSPA5 | L3MBTL1 3660/4885POLB 3817/4885HPGD 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.