Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870554 | 0.78 | RIPK1 (0.50) | RIPK1L3MBTL1CYP2C19MEN1KMT2A | |
| SCHEMBL3000409 | 0.72 | L3MBTL1 (0.52) | RIPK1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL28013833 | 0.68 | POLB (0.51) | RIPK1L3MBTL1CYP2C19POLBALDH1A1 | |
| SCHEMBL4485884 | 0.68 | RIPK1 (0.50) | RIPK1L3MBTL1CYP2C19POLBALDH1A1 | |
| Acetic Acid SCHEMBL11332370 | 0.66 | CYP2C19 (0.57) | L3MBTL1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL681510 | 0.66 | — | — | |
| SCHEMBL6870551 | 0.66 | HPGD (0.51) | RIPK1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL19890825 | 0.66 | RIPK1 (0.59) | RIPK1CYP2C19MEN1KMT2APOLB | |
| SCHEMBL4473902 | 0.66 | RIPK1 (0.51) | RIPK1L3MBTL1CYP2C19POLBRAB9A | |
| SCHEMBL10916089 | 0.66 | NPC1 (0.49) | L3MBTL1CYP2C19MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178835-A1 | NOVEL SUBSTITUTED PIPERIDONES AS HSP INDUCERS | Torrent Pharmaceuticals Ltd (IN) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009004650-A1 | NOVEL SUBSTITUTED PIPERIDONES AS HSP INDUCERS | TORRENT PHARMACEUTICALS LTD. (IN) | 2009-01-08 | — | — | WO | disclosed |