Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28013833 | 0.85 | POLB (0.51) | RIPK1L3MBTL1CYP2C19POLBALDH1A1 | |
| SCHEMBL4485884 | 0.85 | RIPK1 (0.50) | RIPK1L3MBTL1CYP2C19POLBALDH1A1 | |
| SCHEMBL4485726 | 0.81 | RIPK1 (0.47) | RIPK1L3MBTL1CYP2C19POLBALDH1A1 | |
| SCHEMBL3679679 | 0.78 | RIPK1 (0.44) | RIPK1L3MBTL1CYP2C19POLBALDH1A1 | |
| SCHEMBL6438457 | 0.78 | HSD17B10 (0.48) | RIPK1L3MBTL1POLBALDH1A1HPGD | |
| SCHEMBL3000409 | 0.78 | L3MBTL1 (0.52) | RIPK1L3MBTL1POLBALDH1A1HPGD | |
| SCHEMBL28135655 | 0.78 | CYP2C19 (0.50) | RIPK1L3MBTL1CYP2C19POLBALDH1A1 | |
| SCHEMBL27561210 | 0.77 | L3MBTL1 (0.48) | RIPK1L3MBTL1CYP2C19POLBALDH1A1 | |
| SCHEMBL28345914 | 0.76 | ADRA2A (0.44) | RIPK1L3MBTL1CYP2C19POLBALDH1A1 | |
| SCHEMBL17009210 | 0.76 | POLB (0.50) | RIPK1L3MBTL1CYP2C19POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438309-A1 | QUINUCLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS M2 AND/OR M3 MUSCARINIC RECEPTOR INHIBITORS | UCB, S.A. (BE) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003033495-A1 | QUINUCLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS M2 AND/OR M3 MUSCARINIC RECEPTOR INHIBITORS | UCB, S.A. (BE) | 2003-04-24 | — | — | WO | disclosed |