Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 8/20 | 0.41 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410849 | 0.87 | ADRA2A (0.42) | ADRA2AADRA2BDRD5P2RY6PTAFR | |
| SCHEMBL30005761 | 0.83 | PTAFR (0.41) | ADRA2AADRA2BDRD5P2RY6PTAFR | |
| SCHEMBL30006541 | 0.79 | RAB9A (0.48) | ADRA2AADRA2BDRD5P2RY6PTAFR | |
| SCHEMBL10422970 | 0.73 | SMN1; SMN2 (0.48) | ADRA2AADRA2BDRD5P2RY6NPSR1 | |
| SCHEMBL4943682 | 0.71 | PTAFR (0.42) | ADRA2AADRA2BDRD5P2RY6PTAFR | |
| SCHEMBL4942400 | 0.68 | ADRA2A (0.44) | ADRA2AADRA2BDRD5P2RY6PTAFR | |
| SCHEMBL4940343 | 0.68 | ADRA1D (0.43) | ADRA2AADRA2BDRD5P2RY6PTAFR | |
| SCHEMBL15787798 | 0.67 | TACR1 (0.36) | PARK7MEN1KMT2AHPGDNPSR1 | |
| SCHEMBL4578025 | 0.66 | ALDH1A1 (0.47) | NPSR1 | |
| SCHEMBL15787799 | 0.66 | MAPT (0.36) | PARK7MEN1KMT2ACYP1B1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |