Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 8/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410849 | 0.88 | ADRA2A (0.42) | RAB9AADRA2AADRA2BDRD5P2RY6 | |
| SCHEMBL1894591 | 0.83 | RAB9A (0.50) | RAB9AALDH1A1SMN1; SMN2CYP1B1 | |
| SCHEMBL10422970 | 0.82 | SMN1; SMN2 (0.48) | RAB9AADRA2AADRA2BDRD5P2RY6 | |
| SCHEMBL30005761 | 0.82 | PTAFR (0.41) | RAB9AADRA2AADRA2BDRD5P2RY6 | |
| SCHEMBL8902954 | 0.80 | RXFP1 (0.46) | ADRA2AADRA2BDRD5P2RY6PTAFR | |
| SCHEMBL8803206 | 0.79 | MMP2 (0.53) | RAB9AALDH1A1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL30006416 | 0.79 | ADRA2A (0.43) | RAB9AADRA2AADRA2BDRD5P2RY6 | |
| SCHEMBL4943682 | 0.77 | PTAFR (0.42) | RAB9AADRA2AADRA2BDRD5P2RY6 | |
| SCHEMBL4940343 | 0.74 | ADRA1D (0.43) | ADRA2AADRA2BDRD5P2RY6PTAFR | |
| SCHEMBL4947503 | 0.73 | ADRA2A (0.39) | ADRA2AADRA2BDRD5P2RY6PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |