Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930239 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL30211242 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL23958638 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL7566003 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL23930050 | 0.77 | LMNA (0.51) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL30007106 | 0.77 | LMNA (0.51) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL23958774 | 0.76 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL11152604 | 0.75 | TRPM8 (0.60) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL23484393 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL3407583 | 0.74 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |