Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13780197 | 0.86 | ADORA3 (0.74) | ALDH1A1ADORA3KDM4ENPC1MAPT | |
| SCHEMBL15481445 | 0.84 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1ADORA3TRPM8KDM4E | |
| Hydrochloric Acid SCHEMBL10377238 | 0.83 | ADORA3 (0.56) | ALDH1A1ADORA3KDM4ENPC1MAPT | |
| SCHEMBL9788390 | 0.83 | KDM4E (0.64) | ALDH1A1L3MBTL1ADORA3KDM4ENPC1 | |
| SCHEMBL10410199 | 0.81 | EGLN1 (0.48) | KDM4EHTT | |
| SCHEMBL10519868 | 0.78 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1TRPM8KDM4ENPC1 | |
| SCHEMBL6949795 | 0.78 | ADORA3 (0.50) | ALDH1A1L3MBTL1ADORA3TRPM8KDM4E | |
| SCHEMBL28484544 | 0.77 | ADORA2B (0.60) | ALDH1A1L3MBTL1ADORA3TRPM8KDM4E | |
| SCHEMBL23930239 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1ADORA3TRPM8KDM4E | |
| SCHEMBL30007091 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1ADORA3TRPM8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705837-B1 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5744604-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| US-5677455-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0705837-A2 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-4929620-A | ANTILIPEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4868185-A | HYPOLIPIDEMIC, ANTICHOLESTEROL | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |