SCHEMBL31411468

SCHEMBL31411468

Cc1ccc(S(=O)(=O)n2ncc3c(F)c(F)ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.42
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
LMNA P02545 3/20 0.39
HTR6 P50406 2/20 0.38
KMT2A Q03164 3/20 0.38
PTGS2 P35354 2/20 0.38
MEN1 O00255 2/20 0.38
OPRM1 P35372 1/20 0.38
PTGS1 P23219 1/20 0.37
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411304 0.84 MAPT (0.40) SLC9A1MAPTPKMLMNAHTR6
SCHEMBL27087160 0.78 SLC9A1 (0.42) SLC9A1MAPTPKMLMNAHTR6
SCHEMBL30007377 0.78 SLC9A1 (0.42) SLC9A1MAPTPKMLMNAHTR6
SCHEMBL29937166 0.75 OPRM1 (0.51) SLC9A1MAPTHTR6KMT2AMEN1
SCHEMBL14662867 0.74 OPRM1 (0.40) SLC9A1MAPTPKMLMNAHTR6
SCHEMBL31411447 0.74 MAPT (0.40) SLC9A1MAPTPKMLMNAKMT2A
SCHEMBL29804026 0.74 OPRD1 (0.48) SLC9A1MAPTPKMKMT2AMEN1
SCHEMBL12384995 0.73 OPRM1 (0.47) SLC9A1MAPTPKMLMNAHTR6
SCHEMBL20488617 0.72 HTR6 (0.47) SLC9A1PKMHTR6OPRM1
SCHEMBL2992752 0.72 HSD11B1 (0.47) SLC9A1MAPTPKMLMNAHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB SLC9A1 3575/4885MAPT 139/4885PKM 379/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB SLC9A1 3575/4885MAPT 139/4885PKM 379/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB SLC9A1 3575/4885MAPT 139/4885PKM 379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.