Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693347 | 0.85 | PLA2G2A (0.51) | ALDH1A1MEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL2580436 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL29029780 | 0.84 | ADRA1D (0.46) | ALDH1A1MEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL30410966 | 0.84 | ADRA1D (0.46) | ALDH1A1MEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL7054203 | 0.82 | ADRA1D (0.49) | AURKAADRA1D | |
| SCHEMBL7050803 | 0.82 | ADRA1D (0.44) | ALDH1A1MEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL6691732 | 0.82 | ADRA1D (0.44) | ALDH1A1MEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL6774185 | 0.81 | TP53 (0.47) | ALDH1A1MEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL27506423 | 0.81 | ADRA1D (0.43) | ALDH1A1MEN1KMT2AL3MBTL1AURKA | |
| SCHEMBL5388266 | 0.80 | NPSR1 (0.57) | ALDH1A1MEN1KMT2AL3MBTL1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220370411-A1 | EARLY MANAGEMENT, MITIGATION and PREVENTION OF SEPSIS and SEPSIS-LIKE SYNDROMES, INCLUDING NEO-NATAL ARDS DUE TO INFECTION, INJURY or IATROGENESIS | OPHIREX INC (US) | 2022-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220370411-A1 | EARLY MANAGEMENT, MITIGATION and PREVENTION OF SEPSIS and SEPSIS-LIKE SYNDROMES, INCLUDING NEO-NATAL ARDS DUE TO INFECTION, INJURY or IATROGENESIS | PLA2G12A, PLA2G3, PLA2G1B | ALDH1A1 2661/4885MEN1 4857/4885KMT2A 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.