Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187337 | 0.87 | DRD4 (0.30) | — | |
| SCHEMBL20187336 | 0.68 | COMT (0.40) | GAA | |
| Hydrochloric Acid SCHEMBL30007311 | 0.67 | COMT (0.39) | GAA | |
| Trifluoroacetic Acid SCHEMBL22578586 | 0.65 | KIF11 (0.40) | — | |
| SCHEMBL174113 | 0.62 | RXRA (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL22735410 | 0.62 | ALDH1A1 (0.43) | — | |
| SCHEMBL2516540 | 0.61 | POLB (0.44) | GAAKMT2A | |
| Hydrochloric Acid SCHEMBL29002478 | 0.60 | POLB (0.43) | GAAKMT2A | |
| SCHEMBL25719683 | 0.60 | SQOR (0.45) | PDE10AKMT2A | |
| SCHEMBL17821115 | 0.60 | GPBAR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234638-B | Heteroaryl phenoxy benzamide KAPPA opioid ligands | 辉瑞大药厂 | 2022-10-21 | — | — | CN | disclosed |