SCHEMBL30008485

CC[C@H](C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)O)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	4/20	0.62

▸	C5AR1	P21730	1/20	0.62

▸	APLNR	P35414	2/20	0.60

▸	CXCR4	P61073	2/20	0.58

▸	MAPK8	P45983	1/20	0.57

▸	MAPK9	P45984	1/20	0.57

▸	MAPK10	P53779	1/20	0.57

▸	F2	P00734	4/20	0.56

▸	HCRTR1	O43613	1/20	0.56

▸	HCRTR2	O43614	1/20	0.56

▸	GLP1R	P43220	1/20	0.56

▸	NPY1R	P25929	1/20	0.55

▸	NPY2R	P49146	1/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29767745	1.00	CALCR (0.63)	CALCRC5AR1APLNRCXCR4MAPK8
SCHEMBL29767747	0.98	CALCR (0.64)	CALCRC5AR1APLNRCXCR4MAPK8
SCHEMBL31691539	0.97	APLNR (0.61)	CALCRC5AR1APLNRCXCR4MAPK8
SCHEMBL31691514	0.95	APLNR (0.62)	CALCRC5AR1APLNRCXCR4MAPK8
SCHEMBL30444321	0.95	APLNR (0.63)	CALCRC5AR1APLNRCXCR4MAPK8
SCHEMBL30444134	0.94	APLNR (0.63)	CALCRC5AR1APLNRCXCR4MAPK8
SCHEMBL30432875	0.92	CALCR (0.65)	CALCRC5AR1APLNRF2GLP1R
SCHEMBL30565598	0.90	CALCR (0.57)	CALCRHCRTR1HCRTR2
SCHEMBL30565601	0.90	CALCR (0.57)	CALCRHCRTR1HCRTR2
SCHEMBL31182976	0.90	CALCR (0.70)	CALCRAPLNRCXCR4F2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12234300-B2	Conjugated hepcidin mimetics	PROTAGONIST THERAPEUTICS, INC. (US)	2025-02-25	—	—	US	disclosed
EP-4501952-A2	CONJUGATED HEPCIDIN MIMETICS	Protagonist Therapeutics, Inc. (US)	2025-02-05	—	—	EP	disclosed
US-20240226225-A1	CONJUGATED HEPCIDIN MIMETICS	PROTAGONIST THERAPEUTICS, INC. (US)	2024-07-11	—	—	US	disclosed
US-20240209024-A1	CONJUGATED HEPCIDIN MIMETICS	PROTAGONIST THERAPEUTICS, INC.	2024-06-27	—	—	US	disclosed
US-20240018189-A1	CONJUGATED HEPCIDIN MIMETICS	PROTAGONIST THERAPEUTICS, INC. (US)	2024-01-18	—	—	US	disclosed
US-20230295259-A1	Conjugated Hepcidin Mimetics	PROTAGONIST THERAPEUTICS, INC.	2023-09-21	—	—	US	disclosed
US-11753443-B2	Conjugated hepcidin mimetics	PROTAGONIST THERAPEUTICS, INC. (US)	2023-09-12	—	—	US	disclosed
US-11472842-B2	Analogues of hepcidin mimetics with improved in vivo half lives	PROTAGONIST THERAPEUTICS, INC. (US)	2022-10-18	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-11472842-B2	Analogues of hepcidin mimetics with improved in vivo half lives	HAMP, VIP, HDGF	CALCR 141/4885C5AR1 317/4885APLNR 20/4885
US-20240018189-A1	CONJUGATED HEPCIDIN MIMETICS	HAMP, VIP, HDGF	CALCR 148/4885C5AR1 122/4885APLNR 13/4885
US-20230295259-A1	Conjugated Hepcidin Mimetics	HAMP, VIP, HDGF	CALCR 148/4885C5AR1 122/4885APLNR 13/4885
US-20240209024-A1	CONJUGATED HEPCIDIN MIMETICS	HAMP, VIP, HDGF	CALCR 148/4885C5AR1 122/4885APLNR 13/4885
US-12234300-B2	Conjugated hepcidin mimetics	HAMP, VIP, HDGF	CALCR 148/4885C5AR1 122/4885APLNR 13/4885
US-11753443-B2	Conjugated hepcidin mimetics	HAMP, VIP, HDGF	CALCR 148/4885C5AR1 122/4885APLNR 13/4885
US-20240226225-A1	CONJUGATED HEPCIDIN MIMETICS	HAMP, SLC40A1, FTH1	CALCR 966/4885C5AR1 1005/4885APLNR 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.