Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009601 | 0.77 | ALDH1A1 (0.47) | MAPTHPGDKMT2AMEN1BRD4 | |
| SCHEMBL30009284 | 0.77 | KMT2A (0.49) | MAPTHPGDKMT2AMEN1BRD4 | |
| SCHEMBL30009926 | 0.76 | HTT (0.46) | MAPTHPGDKMT2AMEN1 | |
| SCHEMBL30009649 | 0.70 | ACHE (0.41) | MAPTHPGDKMT2AHSD11B1MEN1 | |
| SCHEMBL26688764 | 0.70 | GRIA1 (0.37) | KMT2APYGLPYGMPARK7MEN1 | |
| SCHEMBL30009059 | 0.70 | KMT2A (0.53) | KMT2AMEN1BRD4 | |
| SCHEMBL21680919 | 0.67 | NR1H2 (0.41) | MAPTKMT2AMEN1 | |
| SCHEMBL28250154 | 0.67 | ACHE (0.53) | MAPTHPGDPYGLPYGMBRD4 | |
| SCHEMBL30009915 | 0.66 | ACHE (0.41) | MAPTHPGDKMT2AMEN1 | |
| SCHEMBL19953484 | 0.64 | GRM7 (0.43) | MAPTKMT2APYGLPYGMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141212-A | Synthetic method of benzoazacyclo skeleton containing oxygen bridged ring | 南通大学 | 2022-10-04 | — | — | CN | claimed |
| CN-115141212-A | Synthetic method of benzoazacyclo skeleton containing oxygen bridged ring | 南通大学 | 2022-10-04 | — | — | CN | disclosed |