Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009649 | 0.83 | ACHE (0.41) | KMT2ASMN1; SMN2MEN1L3MBTL1MAPT | |
| SCHEMBL30009926 | 0.79 | HTT (0.46) | KMT2ASMN1; SMN2MEN1L3MBTL1MAPT | |
| SCHEMBL30009368 | 0.77 | MAPT (0.38) | KMT2AMEN1MAPTHPGDBRD4 | |
| SCHEMBL30009915 | 0.76 | ACHE (0.41) | KMT2AGAASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL30009601 | 0.75 | ALDH1A1 (0.47) | KMT2AGAASMN1; SMN2MEN1LMNA | |
| SCHEMBL30009059 | 0.72 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1ALDH1A1PTGDR2 | |
| SCHEMBL4703431 | 0.70 | AADAT (0.44) | KMT2AGAASMN1; SMN2MEN1LMNA | |
| SCHEMBL29915935 | 0.67 | MEN1 (0.52) | KMT2AGAASMN1; SMN2MEN1LMNA | |
| SCHEMBL17974970 | 0.65 | MEN1 (0.49) | KMT2AGAASMN1; SMN2MEN1LMNA | |
| SCHEMBL29557464 | 0.65 | BRD4 (0.49) | KMT2AGAASMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141212-A | Synthetic method of benzoazacyclo skeleton containing oxygen bridged ring | 南通大学 | 2022-10-04 | — | — | CN | claimed |
| CN-115141212-A | Synthetic method of benzoazacyclo skeleton containing oxygen bridged ring | 南通大学 | 2022-10-04 | — | — | CN | disclosed |