Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 4/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009649 | 0.87 | ACHE (0.41) | ACHEAKT1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL30009284 | 0.76 | KMT2A (0.49) | SMN1; SMN2ALDH1A1MAPTGAAHPGD | |
| SCHEMBL30009801 | 0.73 | AKR1C3 (0.44) | SMN1; SMN2ALOX15HSD17B10ALDH1A1MAPT | |
| SCHEMBL30009926 | 0.70 | HTT (0.46) | ACHEPARP1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6608136 | 0.68 | AKR1C3 (0.53) | CYP3A4SMN1; SMN2ALDH1A1MAPTAKR1C3 | |
| SCHEMBL1286677 | 0.68 | ALDH1A1 (0.55) | ALOX15HSD17B10ALDH1A1MAPTAKR1C3 | |
| SCHEMBL28393741 | 0.68 | MAPT (0.53) | CYP3A4SMN1; SMN2ALOX15ALDH1A1MAPT | |
| SCHEMBL226006 | 0.67 | ALDH1A1 (0.57) | CYP3A4SMN1; SMN2ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL29816440 | 0.67 | ALDH1A1 (0.57) | CYP3A4SMN1; SMN2ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL30009368 | 0.66 | MAPT (0.38) | MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141212-A | Synthetic method of benzoazacyclo skeleton containing oxygen bridged ring | 南通大学 | 2022-10-04 | — | — | CN | claimed |