Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009601 | 0.85 | ALDH1A1 (0.47) | HTTALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL30009284 | 0.79 | KMT2A (0.49) | HTTPTGDR2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30009368 | 0.76 | MAPT (0.38) | MAPTMEN1KMT2AHPGD | |
| SCHEMBL6070644 | 0.73 | PTGDR2 (0.70) | PTGDR2MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL5319959 | 0.73 | PTGDR2 (0.70) | PTGDR2MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL6070649 | 0.73 | PTGDR2 (0.70) | PTGDR2MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL30009649 | 0.72 | ACHE (0.41) | ALDH1A1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL30009915 | 0.70 | ACHE (0.41) | ALDH1A1SMN1; SMN2PKMKDM4EMAPT | |
| SCHEMBL30799272 | 0.69 | PIN1 (0.60) | ALDH1A1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL30009669 | 0.69 | CES2 (0.57) | NPC1RAB9AL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141212-A | Synthetic method of benzoazacyclo skeleton containing oxygen bridged ring | 南通大学 | 2022-10-04 | — | — | CN | claimed |
| CN-115141212-A | Synthetic method of benzoazacyclo skeleton containing oxygen bridged ring | 南通大学 | 2022-10-04 | — | — | CN | disclosed |