Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.55 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389279 | 1.00 | GAA (0.73) | GAAMEN1KMT2ATDP1KDM4E | |
| SCHEMBL22234047 | 0.92 | GAA (0.71) | GAAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL29540765 | 0.92 | GAA (0.71) | GAAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL22252009 | 0.84 | GAA (0.60) | GAAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL3258816 | 0.83 | HCRTR1 (0.67) | GAAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13510393 | 0.81 | KEAP1 (0.66) | GAAMEN1KMT2ATDP1KDM4E | |
| SCHEMBL13509802 | 0.81 | PGAM1 (0.60) | GAAMEN1KMT2ATDP1KDM4E | |
| SCHEMBL3984153 | 0.80 | MMP2 (0.65) | GAAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL1507919 | 0.80 | SLC40A1 (0.76) | GAAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL30854809 | 0.80 | SLC40A1 (0.76) | GAAMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111067889-B | Application of 2-methyl naphtho [1,2-b ] furan compound in preparation of medicine related to diabetic nephropathy | 徐州医科大学 | 2022-11-18 | — | — | CN | disclosed |