Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614304 | 0.84 | ACHE (0.46) | HTR2AKCNH2 | |
| SCHEMBL21093634 | 0.76 | GRIN2B (0.44) | GRIN2BKCNH2 | |
| SCHEMBL7810455 | 0.76 | GRIN2B (0.46) | GRIN2B | |
| SCHEMBL30009848 | 0.74 | AKR1C3 (0.47) | HTR2AGRIN2BKCNH2 | |
| SCHEMBL21093397 | 0.73 | ALDH1A1 (0.43) | GRIN2BOPRM1 | |
| SCHEMBL12050567 | 0.73 | ACHE (0.46) | HTR2AKCNH2RAB9A | |
| SCHEMBL21494357 | 0.72 | ALDH1A1 (0.49) | GRIN2B | |
| SCHEMBL25239236 | 0.70 | CYP2C9 (0.44) | GRIN2BOPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL18681661 | 0.70 | ACHE (0.44) | HTR2AKCNH2 | |
| SCHEMBL25740889 | 0.70 | ACHE (0.44) | HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141212-A | Synthetic method of benzoazacyclo skeleton containing oxygen bridged ring | 南通大学 | 2022-10-04 | — | — | CN | disclosed |